From: Production, purification, and radiolabeling of the 203Pb/212Pb theranostic pair
203Pb-complex % stable | Time point | |||
---|---|---|---|---|
8 h | 24 h | 48 h | 72 h | |
[203Pb][Pb(TCMC)]2+ | 98.0 ± 0.5% | 98.1 ± 0.2% | 98.2 ± 0.3% | 97.2 ± 0.7% |
[203Pb][Pb(DOTA)]2− | 97.1 ± 0.7% | 97.3 ± 0.6% | 98.1 ± 0.2% | 97.4 ± 0.5% |
[203Pb][Pb(DOTA-1Py)]− | 97.4 ± 0.4% | 97.7 ± 0.3% | 98.1 ± 0.4% | 97.5 ± 0.7% |
[203Pb][Pb(DOTA-2Py)] | 97.7 ± 0.1% | 97.8 ± 0.1% | 97.8 ± 0.9% | 97.1 ± 0.2% |
[203Pb][Pb(DOTA-3Py)]+ | 98.4 ± 0.3% | 98.0 ± 0.4% | 98.4 ± 0.1% | 97.7 ± 0.3% |
Negative Control | 1.2 ± 0.3% | 1.4 ± 0.2% | 1.4 ± 0.2% | 1.5 ± 0.2% |