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Fig. 3 | EJNMMI Radiopharmacy and Chemistry

Fig. 3

From: Highlight selection of radiochemistry and radiopharmacy developments by editorial board (January–June 2020)

Fig. 3

PET imaging characteristics of [11C]K-2 in patients with epilepsy. A: Presurgical MRI and PET images used to examine the correlation between AMPA receptor expression and retention of [11C]K-2 in patient with MTLE. VOIs on individual MRI images were defined within the outline of expected resection areas (left). B: Representative immunoblot of resected brain tissues in a patient with MTLE performed with a pan-AMPA receptor antibody. The origins of the samples are listed on the right, corresponding to the numbers on the blot and VOI identifications. C: Correlations between SUVR30-50min for [11C]K-2 and the biochemical amount of AMPA receptor (OD) in multiple brain regions form patients with MTLE. D: SUVR30-50min images of [11C]K-2 were obtained from 6 patients with MTLE. White arrows indicate the epileptogenic foci. This figure was obtained from Miyazaki et al. (2020) which was licensed under a Creative Commons License http://creativecommons.org/licenses/by/4.0/

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