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Table 3 Trialled reaction conditions for model systems

From: Automated synthesis of 18F radiolabelled indole containing Oncrasin-like molecules; a comparison of iodonium salts and boronic ester chemistry

Reaction

1

2

3

4

5

Eluent

Carbonate

Tetrabutylamine

Bicarbonate

None

Triflate

Catalyst

Tetrakis Complex

Tetrakis Complex

Tetrakis Complex

Cu(OTf)2 + Pyridine

Cu(OTf)2 + Pyridine

Kryptofix

10 mg

4.5 mg

 

4.5 mg

Outcome

Nil

Nil

Nil

Minor Product

Product