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EJNMMI Radiopharmacy and Chemistry

Table 2 Reaction conditions trialled with for iodonium salt synthesis

From: Automated synthesis of 18F radiolabelled indole containing Oncrasin-like molecules; a comparison of iodonium salts and boronic ester chemistry

Oxidant

Counter ion

Aryl System

MCPBA

OTf/OTs

p-Methoxybenzene (Bielawski et al. 2007)

Peroxide

OTs

1,3, Dimethoxy Benzene

Oxone

OTs

1,3,5 Trimethoxy Benzene

Sodium Periodate (Kazmierczak et al. 2001)

Acetic acid/H2SO4

1,3,5 Trimethoxy Benzene

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