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Table 2 Comparison of residual TBA, MeCN, DMSO, and ethanol among three cassette types

From: Automated [18F]PSMA-1007 production by a single use cassette-type synthesizer for clinical examination

Cassette material Fluoro-elastomer
(n = 3)
PharMed® BPT
(n = 3)
Silicone
(n = 3)
Silicone
(n = 7)
Precursor form TFA salt TFA salt TFA salt ACE salt
Residual TBA (μg/mL) <  2.6 <  2.6 <  2.6 <  2.6
Residual MeCN (ppm) <  8 <  8 <  8 <  8
Residual DMSO (ppm) <  11 <  11 <  11 <  11
Ethanol (v/v %) 8.1 ± 0.2 8.0 ± 0.1 8.0 ± 0.2 7.8 ± 0.1