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EJNMMI Radiopharmacy and Chemistry

Table 2 Comparison of residual TBA, MeCN, DMSO, and ethanol among three cassette types

From: Automated [18F]PSMA-1007 production by a single use cassette-type synthesizer for clinical examination

Cassette material

Fluoro-elastomer

(n = 3)

PharMed® BPT

(n = 3)

Silicone

(n = 3)

Silicone

(n = 7)

Precursor form

TFA salt

TFA salt

TFA salt

ACE salt

Residual TBA (μg/mL)

<  2.6

<  2.6

<  2.6

<  2.6

Residual MeCN (ppm)

<  8

<  8

<  8

<  8

Residual DMSO (ppm)

<  11

<  11

<  11

<  11

Ethanol (v/v %)

8.1 ± 0.2

8.0 ± 0.1

8.0 ± 0.2

7.8 ± 0.1

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