Production of radiometals in liquid targets

EJNMMI Radiopharmacy and Chemistry

Table 2 Generator-produced radiometals with clinical potential

Generator	Parent	Daughter nuclide								References
	nuclide	Half-life	β⁻ end-point	Average	Maximum	Average	Electron	Typical activity	Generator
	nuclide		energy	β⁻ energy	β⁺ energy	β⁺ energy	Capture	per elution	longevity
	Half-life		(keV)	(keV)	(keV)	(keV)	(%)	(GBq)
⁴⁴Ti/⁴⁴Sc	60,6 y	3,97 h			1474 (94,3%)	632	5,7	0,18	1–2 years	(Pruszynski et al. 2010; Filosofov et al. 2010)
⁶²Zn/⁶²Cu	9,26 h	9,74 min			2910(98%)		2	1,2	1 day	(Anderson et al. 2003; Haynes et al. 2000)
⁶⁸Ge/⁶⁸Ga	271 d	1,14 h			821,7 (1,2%)	352,6	11,1	0,370-1,85	1–2 years	(Fani et al. 2008)
⁶⁸Ge/⁶⁸Ga					1899 (88,9%)	836,0
⁸²Sr/⁸²Rb	25,6 d	1,26 min			2604 (13,1%)	1168	4,35	200	1–6 months	(Phillips et al. 2000)
⁸²Sr/⁸²Rb					3381 (81,2%)	1535			1–6 months
⁹⁰Sr/⁹⁰Y	28,6 y	64,1 h	518 (0,02%)	163,7				18,5	tens of years	(Chakravarty et al. 2008)
⁹⁰Sr/⁹⁰Y			2279 (99,9%)	926,7				18,5	tens of years	(Chakravarty et al. 2008)
¹⁸⁸W/¹⁸⁸Re	69,4 d	17,0 h	1487 (1,6%)	527,8				20	10 months	(Dasha and Knapp Jr 2015)
			1965 (25,6%)	728,9
			2120 (71,1%)	795,4