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Fig. 3 | EJNMMI Radiopharmacy and Chemistry

Fig. 3

From: Automated GMP compliant production of [18F]AlF-NOTA-octreotide

Fig. 3

Representative chromatogram (220 nm) of the reference solution (A) and radiochromatogram of [18F]AlF-NOTA-octreotide at the end of synthesis (b). a) Peak 1 (16.4 min) corresponds to NOTA-octreotide, peak 2 (18.1 min) corresponds to octreotide and peak 3 (19.8 min) corresponds to Fe-NOTA-octreotide. b) [18F]AlF-NOTA-octreotide elutes as two stereoisomers (Peak 7: 21.9 min and Peak 8: 24.4 min), Peak 1 (0.8 min) corresponds to free 18F/Al18F and Peaks 2–6 and 9–11 correspond to radiolytic degradation products of [18F]AlF-NOTA-octreotide

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