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EJNMMI Radiopharmacy and Chemistry
Fig. 4 | EJNMMI Radiopharmacy and Chemistry

Fig. 4

From: Evaluation of polydentate picolinic acid chelating ligands and an α-melanocyte-stimulating hormone derivative for targeted alpha therapy using ISOL-produced 225Ac

Fig. 4

Radiochemical yields (RCY, %) for 225AcIII radiolabeling reactions of DOTA (RT, 2 h, pH 5.5; 85 °C, 30 min, pH 7, H4octapa (RT, 1 h, pH 5.5), H3CHXoctapa (RT, 1 h, pH 5.5), H4neunpa (RT, 1 h, pH 5.5), H6phospa (RT, 1 h, pH 5.5), H2bispa2 (RT, 1 h, pH 5.5) and macropa (RT, 5 min, pH 7) for comparison, at ambient temperature (RT) and ligand concentrations 10− 3 to 10− 8 M

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