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Fig. 2 | EJNMMI Radiopharmacy and Chemistry

Fig. 2

From: Evaluation of polydentate picolinic acid chelating ligands and an α-melanocyte-stimulating hormone derivative for targeted alpha therapy using ISOL-produced 225Ac

Fig. 2

225Ra/225Ac radiochemical separation method used for purification of ISOL-produced 225Ac. The solution resulting from etching 225Ra and 225Ac from the aluminum target was diluted with nitric acid (to 4 M HNO3) and loaded onto a preconditioned DGA resin (Horwitz et al. 2005). After washing the resin (with 4 M HNO3) to remove residual 225RaII, the 225AcIII was eluted from the resin 0.5 mL of 0.05 M HNO3

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