Fig. 3From: Synthesis of a benzoxazinthione derivative of tanaproget and pharmacological evaluation for PET imaging of PR expressionIn vitro characterisation of [18F]2 in breast cancer cell lines with varying PR expression levels. a Western Blot showing PR expression in cell lines and in ovarian of C57BL/6 female mice with or without gonadotropic stimulation of PR expression (+/− HT). b Uptake of [18F]2 in three cell lines. c Blocking [18F]2 uptake in T47D cells treated with progesterone (0.01–1 μM). Error bars indicate standard errors from n = 3 repeats. Significances are marked with asterisk, (*) and (**) P ≤ 0.05, P ≤ 0.01, respectivelyBack to article page