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Table 3 Percentage of intact tracer in plasma and brain after 10 and 45 min (N = 2)

From: Synthesis and preliminary preclinical evaluation of fluorine-18 labelled isatin-4-(4-methoxyphenyl)-3-thiosemicarbazone ([18F]4FIMPTC) as a novel PET tracer of P-glycoprotein expression

  % intact [18F]5 % intact [18F]6
10 min
 Plasma 21.5 ± 0.7 14.0 ± 2.8
 Brain 62.5 ± 6.4 20.5 ± 0.7
45 min
 Plasma 11.5 ± 2.1 7.0 ± 0.0
 Brain 68.5 ± 2.1 16.0 ± 0.7