From: Synthesis and preliminary preclinical evaluation of fluorine-18 labelled isatin-4-(4-methoxyphenyl)-3-thiosemicarbazone ([18F]4FIMPTC) as a novel PET tracer of P-glycoprotein expression
Solvent 0.5 mL
Precursor
(μmol)
Temperature
(°C)
Kryptofix
K2CO3
Yield
(%)
DMSO
26
120
6
3
6%
24
140
7%
54
5%
160
4%
MeCN
1%
18
9
2%
16
3%