Skip to main content
EJNMMI Radiopharmacy and Chemistry

Table 3 Metabolites of (S)-[18F]9a in plasma, kidney, urine, liver, muscle and brain

From: Synthesis, radiosynthesis, in vitro and first in vivo evaluation of a new matrix metalloproteinase inhibitor based on γ-fluorinated α-sulfonylaminohydroxamic acid

30 min p.i.

Organ/tissue/body fluid (% HPLC)

Plasma

Kidney

Urine

Liver

Muscle

Brain

(S)-[18F]9a: tR ≈ 10.3 min

8

17

–

1

17

12

metabolite 1: tR ≈ 2.0 min

81

66

76

4

83

88

metabolite 2: tR ≈ 3.9 min

6

–

9

 

–

–

metabolite 3: tR ≈ 5.5 min

2

–

9

 

–

–

metabolite 4: tR ≈ 9.5 min

–

17

6

94

–

–

metabolite 5: tR ≈ 11.4 min

3

–

–

1

–

–

Back to article page