Fig. 5

Representative radio-HPLC traces for 30 min p.i. of the metabolism study of (S)-[18F]9a. The radiochemical purity of (S)-[18F]9a was > 97% before injection. The samples were analyzed by HPLC, using a γ-detector (Raytest Isotopenmessgeräte GmbH/Agilent). The HPLC was done on a Phenomenex C18 column (250 × 4.6 mm) using a gradient method with acetonitrile and water (both having 0.05% TFA)