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Table 2 Concentrations and identification of FDOPA and L-DOPA (g/l) and side products in FDOPA-L and FDOPA-H batches analyzed with UPLC-MS (both n = 6)

From: Improved GMP-compliant multi-dose production and quality control of 6-[18F]fluoro-L-DOPA

FDOPA-L
MC17- cyclotron FDOPA
214.052 Da
(g/L)
L-DOPA
196.061 Da
(g/L)
6-hydroxy-DL-DOPA
212.056 Da
FDOPA-quinone
212.036 Da
 X ± SD 1.21 ± 0.15 0.04 ± 0.04 - +
FDOPA-H
Cyclone 18 twin cyclotron FDOPA
214.052 Da
(g/L)
L-DOPA
196.061 Da
(g/L)
6-hydroxy-DL-DOPA
212.056 Da
FDOPA- quinone
212.036 Da
 X ± SD 0.53 ± 0.10 0.007 ± 0.003 - -
  1. + = side product detected and – means not detectable