Table 1 Overview of the different treatment groups (* saline treatment, equivalent volumes)
Experiment | Treatment | Injection route | Dose (mg/kg) | Duration of treatment | Time before scan | n |
|---|---|---|---|---|---|---|
1 | Amphetamine | SC | 5 | Acute | 60Â min | 6 |
2 | Amphetamine | IV | 1 | Acute | 5Â min | 5 |
3 | Saline (test/retest) | SC | * | Acute | 60Â min | 3 |
4 | Saline (test/retest) | IV | * | Acute | 5Â min | 3 |
5 | Amphetamine | SC | 5 | 5Â days | 4Â h | 5 |
6 | Amphetamine + SCH23390 | SC | 5 1 | 5Â days | 4Â h | 6 |
7 | SCH23390 | SC | 1 | 5Â days | 4Â h | 5 |
8 | Saline | SC | * | 5Â days | 4Â h | 3 |