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Table 1 Stability of 225Ac- and 111In-labeled DO3A-BODIPY-Tz (13) complexes in human serum at 37 °C (n = 3)

From: Development of a multi faceted platform containing a tetrazine, fluorophore and chelator: synthesis, characterization, radiolabeling, and immuno-SPECT imaging

 

Time point (d)

% intact

0.2

1

3

4

5

6

111In-13

NDa

87 ± 4

70 ± 2

NDa

NDa

50 ± 1

225Ac-13

98 ± 1

84 ± 1

69 ± 2

61 ± 5

54 ± 1

NDa

  1. aND = not determined