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Table 3 Overview of stability studies with activity investigated, temperature, amount of ethanol, quality references and shelf life.

From: Stability evaluation of [18F]FDG: literature study, stability studies from two different PET centres and future recommendations

Study Activity GBq/mL Temperature Ethanol (%) Quality references Shelf life
Ferreira et al. (2009) 0.3–0.7 RT (22 °C) ≈ 0.04 USP 31 10 h
Walters et al. (2011) 19.7–22.6 EOS 0.2 USP 34 12 h
Dantas et al. (2013) 0.7–4.8 5, 25, 40 °C 0.1-0.4 Ph. Eur. 7ed 16 h
Rahmani et al. (2017) 0.3–0.5 18–23 °C, 35–40 °C 0.012 mg/mL Ph. Eur. 7ed 10 h
Jószai et al. (2019) 2 and 15 RT 50 mmol/L Ph. Eur. 9ed 210 min or 15 h
Kiselev et al. (2006) min. 0.01%/GBq/mL
Fawdry (2007) 6.3 and 11.5 RT 0.1 BP 2005 14 h
Jacobson et al. (2009) up to 14.2 0.1 Ph. Eur. 6ed 10 h
Rensch et al. (2012) 4–23 14 h
Long et al. (2013) 2.26–8.8 0.2 ± 0.07 USP 34