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EJNMMI Radiopharmacy and Chemistry
Fig. 3 | EJNMMI Radiopharmacy and Chemistry

Fig. 3

From: A suitable time point for quantifying the radiochemical purity of 225Ac-labeled radiopharmaceuticals

Fig. 3

taken from the same reaction at different time points joined by a curve. aDOTA-containing ligands (RPS-072, EuK-106, EuK-107). b Macropa-containing ligands (RPS-074, RPS-088, RPS-092). c All compounds

Plot of radiolabeling yield versus measurement time after TLC for multiple reaction conditions. Radiolabeling was performed using RPS-072, RPS-074, RPS-088, RPS-092, EuK-106, or EuK-107 and [225Ac]AcCl3 in 1 M NH4OAc. Conditions are described in Table 1. Activity distribution on the TLC plates was visualized at the specified times using a Cyclone Plus Storage Phosphor System. Quantification of labeling was performed using OptiQuant™ software. Each data point represents a unique measurement, with measurements

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