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Table 3 Radiochemical purity of [99mTc]Tc-NanoHSA. RCP determined with iTLC and SPE for three individual radiolabellings (n = 3) carried out on three consecutive days

From: An investigation of aspects of radiochemical purity of 99mTc-labelled human serum albumin nanocolloid

  MEK
iTLC-SG
85% Methanol / H2O
iTLC-SG
0.9% NaCl
iTLC-SA
Sep-Pak®
t0 99.7 ± 0.2 96.2 ± 0.3 96.5 ± 0.3 95.7 ± 0.1#
+ 30 min 99.9 ± 0.1 98.1 ± 0.4 98 ± 0.1 97.6 ± 0.0*
+ 60 min 100 ± 0.1 98.6 ± 0.1 98.7 ± 0.0 98.3 ± 0.1*
  1. #n = 3 Sep-Pak® experimental replicates *n = 2 Sep-Pak® experimental replicates