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Table 3 Radiochemical purity of [99mTc]Tc-NanoHSA. RCP determined with iTLC and SPE for three individual radiolabellings (n = 3) carried out on three consecutive days

From: An investigation of aspects of radiochemical purity of 99mTc-labelled human serum albumin nanocolloid

 

MEK

iTLC-SG

85% Methanol / H2O

iTLC-SG

0.9% NaCl

iTLC-SA

Sep-Pak®

t0

99.7 ± 0.2

96.2 ± 0.3

96.5 ± 0.3

95.7 ± 0.1#

+ 30 min

99.9 ± 0.1

98.1 ± 0.4

98 ± 0.1

97.6 ± 0.0*

+ 60 min

100 ± 0.1

98.6 ± 0.1

98.7 ± 0.0

98.3 ± 0.1*

  1. #n = 3 Sep-Pak® experimental replicates *n = 2 Sep-Pak® experimental replicates