Skip to main content
EJNMMI Radiopharmacy and Chemistry

Table 1 Synthesis of 6-[18F]FDOPA 1 starting from different precursors using chiral auxiliaries

From: Advances in the automated synthesis of 6-[18F]Fluoro-L-DOPA

Entry

Precursor

Time (min)

RCY (%)

Am (GBq/μmol)

ee (%)

Ref.

1

110

5–10

n.d.

83–96

(Lemaire et al., 1993)

2

85

6–13

> 74

98

(Najafi, 1995)

3

100–110

12

n.d.

n.d.

(Ding et al., 1990)

4

90

17–29a

> 37

> 96

(Lemaire et al., 1994)

  1. Unless otherwise stated, RCYs are given non-decay corrected (ndc). adecay corrected (dc); n.d: not determined
Back to article page