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Fig. 3 | EJNMMI Radiopharmacy and Chemistry

Fig. 3

From: Design of PSMA ligands with modifications at the inhibitor part: an approach to reduce the salivary gland uptake of radiolabeled PSMA inhibitors?

Fig. 3

Biodistribution data (% ID/g) of [177Lu]Lu-PSMA-10 ([177Lu]Lu-1), [177Lu]Lu-5, [177Lu]Lu-6 and [177Lu]Lu-7 in tumor xenograft-bearing CB17-SCID mice at 24 h p.i. (n = 2 for [177Lu]Lu-5*, n = 3 for [177Lu]Lu-6 and [177Lu]Lu-7 and n = 5 for [177Lu]Lu-PSMA-10 ([177Lu]Lu-1)). Submandibular and parotid glands were dissected separately and their values are depicted in the columns ‚GL. SUBMAND.‘and ‚GL. PAROTIDEA‘, respectively. *Ingestion of radioactively contaminated animal feed led to putative high activities in stomach and intestine, therefore excluding all values of mouse 3

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