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Fig. 1 | EJNMMI Radiopharmacy and Chemistry

Fig. 1

From: Automated synthesis of [18F]Ga-rhPSMA-7/ -7.3: results, quality control and experience from more than 200 routine productions

Fig. 1

Structural formula of the radiohybrid PSMA-targeted ligand [18F]Ga-rhPSMA-7 equipped with a Silicon-Fluoride Acceptor for 18F-labeling in an isotopic exchange reaction. [18F]Ga-rhPSMA-7 represents a mixture of four stereoisomers (7.1, 7.2, 7.3, 7.4), differing in the stereoconfiguration of the diaminopropionic acid branching unit (D-Dap or L-Dap) and the glutamic acid pendant arm at the DOTA-GA-chelator (R-DOTA-GA or S-DOTA-GA; DOTA-GA: 2-(4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododecan-1-yl)pentanedioic acid)

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