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Fig. 7 | EJNMMI Radiopharmacy and Chemistry

Fig. 7

From: Synthesis and validation of [18F]mBPET-1, a fluorine-18 labelled mTOR inhibitor derivative based on a benzofuran backbone

Fig. 7

EC50 values in 4 different breast cancer cell lines treated with RAD001 for 3 days (a). Cell pellet uptake of [18F]mBPET-1 in HCC-1419 and MDA-MB-468 cells over time (b). Unblocked and blocked (treated with 10 μM mBRef-1) uptake of [18F]mBPET-1 in the cell pellet and on the cell surface of 4 different breast cancer cell lines after 2 h (c). Cell pellet uptake of [18F]mBPET-1 in 4 different breast cancer cell lines at 2 h (d). Data are expressed as mean ± SD

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