Table 2 Produced activities at end of synthesis (EOS, not decay corrected) and associated AMA and purities for [⁶⁸Ga]Ga-PSMA-11 and [⁶⁸Ga]Ga-DOTATATE. n: Amount of peptide used for radiolabelling. TLC and TLC (colloid) denominates the RCP of [⁶⁸Ga]Ga-PSMA-11 from analysis for free and colloid gallium-68, respectively

[⁶⁸Ga]Ga-PSMA-11

Activity at EOS

n

AMA at EOS

RCP (HPLC)

TLC

TLC (colloid)

GBq

nmol

MBq/nmol

%

%

%

39.8

100

398

99.9

100

99.7

42.9

100

429

99.8

100

99.9

72.2

100

722

98.2

100

99.8

Average:

99.3

100

99.8

Std.dev.:

1.0

0

0.1

[⁶⁸Ga]Ga-DOTATATE

Activity at EOS

n

AMA at EOS

RCP (HPLC)

ITLC

GBq

nmol

MBq/nmol

%

%

0.87

34.8 (50 µg)

25

97.3

98.4

0.88

34.8 (50 µg)

25

98.2

98.4

0.75

34.8 (50 µg)

23

99.7

99.6

3.22

348 (500 µg)

9.2

95.4

97.1

Average:

97.7

98.4

Std.dev.:

2.2

1.2