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Fig. 3 | EJNMMI Radiopharmacy and Chemistry

Fig. 3

From: Development of a fluorine-18 radiolabelled fluorescent chalcone: evaluated for detecting glycogen

Fig. 3

Correlation of [18F]5 uptake to total glycogen level among a panel of cancer cell lines. a Total intracellular glycogen levels determined by a modified glucose (GO) assay kit. Cells were seeded in 6-well plates at appropriate densities and allowed to attach overnight before determination of glycogen levels. Data are mean ± SD (n = 3); b In vitro uptake of [18F]5. Cells under the same culturing conditions were incubated with fresh DMEM media containing 0.74 MBq [18F]5 for 1 h at 37 °C in a humidified atmosphere of 5% CO2. Data are mean ± SD (n = 6), expressed as % of incubated radioactive dose, normalized to protein content (%ID/mg). c Correlation between total glycogen levels and [18F]5 uptake. The best-fit line is shown with a correlation coefficient (r) = − 0.18 or R2 = 0.03

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