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Table 1 Parameters required for the validation of the HPLC method

From: New sensitive method for HEPES quantification in 68Ga-radiopharmaceuticals

 RequirementsResults
Retention time< 4 min2.8 min
Intra-day
RepeatabilityRSD < 5.00%2.30%
Noise> 1043
Inter-day
ReproducabilityF-test> 0.05F-Test > 0.65
Linearity UV-detectorR2 > 0.98R2 = 0.99
LOD3x noise2.74 ± 0.24
LOQ10x noise9.40 ± 1.25
Carry over≤0.10%0.08%