Table 2 18F-elution varying SPE cartridges, cartridge preconditioning, and the amount of Cu(OTf)2 or Cu(OTf)2(py)4
Entry (n = 3) | Cartridge | Cartridge pre-conditioning | Elution agent | Amount of the elution agent [μmol] | [18F]Fluoride recovery ± SD [%] | EEa ± SD [%] |
|---|---|---|---|---|---|---|
1 | QMA 130 mg | 0.5 M LiOTf, H2O | Cu(OTf)2(py)4 | 24 | 47.1 ± 9.7 | 52.1 ± 11.3 |
2 | QMA 130 mg | 0.5 M LiOTf, H2O | Cu(OTf)2(py)4 | 48 | 52.5 ± 5.0 | 58.5 ± 7.5 |
3 | QMA 130 mg | 0.5 M LiOTf, H2O | Cu(OTf)2(py)4 | 96 | 64.3 ± 10.1 | 68.1 ± 10.0 |
4 | QMA 130 mg | 0.5 M LiOTf, H2O | Cu(OTf)2 | 24 | 48.6 ± 0.6 | 53.4 ± 1.3 |
5 | QMA 130 mg | 0.5 M LiOTf, H 2 O | Cu(OTf) 2 | 48 | 61.8 ± 9.1 | 69.2 ± 9.5 |
6 | QMA 130 mg | 0.5 M LiOTf, H2O | Cu(OTf)2 | 96 | 65.8 ± 7.9 | 70.7 ± 7.1 |
7 | PS-HCO 3 45 mg | H 2 O | Cu(OTf) 2 (py) 4 | 12 | 24.2 ± 6.8 | 26.6 ± 7.3 |
8 | PS-HCO3 45 mg | H2O | Cu(OTf)2(py)4 | 24 | 31.6 ± 9.1 | 35.3 ± 10.6 |
9 | PS-HCO3 45 mg | H2O | Cu(OTf)2(py)4 | 48 | 57.3 ± 4.9 | 63.5 ± 5.9 |
10 | PS-HCO3 45 mg | H2O | Cu(OTf)2 | 12 | 31.9 ± 18.8 | 35.6 ± 20.4 |
11 | PS-HCO3 45 mg | H2O | Cu(OTf)2 | 24 | 41.1 ± 7.5 | 49.1 ± 8.6 |
12 | PS-HCO3 45 mg | H2O | Cu(OTf)2 | 48 | 58.7 ± 9.0 | 64.5 ± 8.9 |
13 | QMA 10 mg | 0.5 M LiOTf, H2O | Cu(OTf)2(py)4 | 12 | 27.5 ± 8.3 | 31.4 ± 11.4 |
14 | QMA 10 mg | 0.5 M LiOTf, H2O | Cu(OTf)2(py)4 | 24 | 34.4 ± 8.8 | 40.5 ± 14.8 |
15 | QMA 10 mg | 0.5 M LiOTf, H2O | Cu(OTf)2(py)4 | 48 | 46.1 ± 9.9 | 52.9 ± 15.9 |
16 | QMA 10 mg | 0.5 M LiOTf, H2O | Cu(OTf)2 | 12 | 32.6 ± 13.4 | 38.8 ± 17.7 |
17 | QMA 10 mg | 0.5 M LiOTf, H2O | Cu(OTf)2 | 24 | 42.7 ± 6.3 | 50.4 ± 8.8 |
18 | QMA 10 mg | 0.5 M LiOTf, H2O | Cu(OTf)2 | 48 | 55.3 ± 3.6 | 62.8 ± 4.8 |
19 | QMA carb 46 mg | H2O | Cu(OTf)2(py)4 | 48 | 38.7 ± 2.3 | 40.5 ± 3.1 |
20 | QMA carb 46 mg | H2O | Cu(OTf)2 | 48 | 29.8 ± 5.8 | 32.1 ± 6.7 |
21 | QMA carb 46 mg | 0.5 M LiOTf, H2O | Cu(OTf)2(py)4 | 48 | 33.2 ± 5.4 | 35.1 ± 6.3 |
22 | QMA carb 46 mg | 0.5 M LiOTf, H2O | Cu(OTf)2 | 48 | 29.4 ± 11.3 | 31.4 ± 13.2 |