Table 4 Stability of ²²⁵Ac-Labelled Chelate Complexes in 50-fold excess La^III at ambient temperature

[²²⁵Ac(octapa)]⁻ (n = 2)

78.9 ± 2.9

42.7 ± 0.3

4.7 ± 1.5

6.1 ± 2.6

ND^a

ND^a

ND^a

[²²⁵Ac(CHXoctapa)]⁻ (n = 2)

ND^a

81.8 ± 4.3

45.7 ± 3.1

26.5 ± 8.9

18.1 ± 0.4

5.0 ± 0.4

3.9 ± 0.6

[²²⁵Ac(phospa)]³⁻ (n = 3)

0

0

ND^a

ND^a

ND^a

ND^a

ND^a

[²²⁵Ac(DOTA)]⁻ (n = 2)

95.2 ± 3.3

94.5 ± 3.5

94.9 ± 2.9

86.2 ± 3.1

ND^a

ND^a

77.1 ± 3.6

[²²⁵Ac(macropa)]⁺ (Thiele et al. 2017)

95

ND^a

93

92

91

93

91^b

[²²⁵Ac(bispa²)]⁺ (Comba et al. 2017)

ND^a

95.5 ± 0.2

91.5 ± 0.7

88.8 ± 2.5

85.2 ± 1.7

74.4 ± 1.4

71.1 ± 2.7