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EJNMMI Radiopharmacy and Chemistry
Fig. 5 | EJNMMI Radiopharmacy and Chemistry

Fig. 5

From: Synthesis, radiosynthesis, in vitro and first in vivo evaluation of a new matrix metalloproteinase inhibitor based on γ-fluorinated α-sulfonylaminohydroxamic acid

Fig. 5

Representative radio-HPLC traces for 30 min p.i. of the metabolism study of (S)-[18F]9a. The radiochemical purity of (S)-[18F]9a was > 97% before injection. The samples were analyzed by HPLC, using a γ-detector (Raytest Isotopenmessgeräte GmbH/Agilent). The HPLC was done on a Phenomenex C18 column (250 × 4.6 mm) using a gradient method with acetonitrile and water (both having 0.05% TFA)

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