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Fig. 4 | EJNMMI Radiopharmacy and Chemistry

Fig. 4

From: Synthesis, radiosynthesis, in vitro and first in vivo evaluation of a new matrix metalloproteinase inhibitor based on γ-fluorinated α-sulfonylaminohydroxamic acid

Fig. 4

In vivo biodistribution of radioactivity in an adult C57/Bl6 mouse after intravenous injection of (S)-[18F]9a. a) Time-activity concentration curves illustrate tracer dynamics in selected regions of interests (ROI). b) Time-activity curves of tissue compartments involved in tracer elimination (liver, gall bladder, intestine, kidneys, bladder) demonstrate predominant hepatobiliary clearance of (S)-[18F]9a from the mouse body. % ID/mL: percentage injected dose per milliliter

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