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Table 2 Stability of the radiopharmaceutical in human plasma and in the final formulation up to 4 hs

From: Synthesis of an Al18F radiofluorinated GLU-UREA-LYS(AHX)-HBED-CC PSMA ligand in an automated synthesis platform

Time (post synthesis) (hours)

Radiochemical purity in the final formulation at room temperature (%) (n = 3)

Radiochemical purity in human plasma at 37 °C (%) (n = 3)

1

94.6 ± 1.8

91.0 ± 0.8

2

92.8 ± 2.5

65.3 ± 3.2

3

93.7 ± 2.0

35.4 ± 1.9

4

94.2 ± 2.8

22.3 ± 2.6