Fig. 7From: 44Sc for labeling of DOTA- and NODAGA-functionalized peptides: preclinical in vitro and in vivo investigationsPET/CT scans of U87MG tumor-bearing mice 5 h after injection of ~10 MBq (~1 nmol) 44Sc-DOTA-RGD (a) and ~10 MBq (~1 nmol) 44Sc-NODAGA-RGD (b). PET/CT scans of AR42J tumor-bearing mice 5 h after injection of ~10 MBq (~1 nmol) 44Sc-DOTA-NOC (c) and ~10 MBq (~3 nmol) 44Sc-NODAGA-NOC (d). During the PET (20 min) and the CT (1.5 min) scans the mice were anesthetized with isoflurane/oxygen (Tu = U87MG (a/b) or AR42J tumor xenografts (c/d), Ki = kidney, Int = intestines, Bl = urinary bladder)Back to article page